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In addition, photomicrograph of testicular tissue section of rat in BPA aged-challenged group showed disturbed architecture of seminiferous tubules, present separation of spermatogonia from the basement membrane and degenerated germinal epithelium (spermatogonia, spermatocytes and spermatids), with small dark nucleus and eosinophilic cytoplasm, others tubules reveal reduction in the number of germinal epithelium cells, degeneration of interstitial tissue and thickened congested blood vessel

Acknowledgements The authors acknowledge and extend their appreciation to the Researchers Supporting Project Number (RSPD2024R709), King Saud University, Riyadh, Saudi Arabia for funding this study