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Ipamorelin produced a selective and dose-dependent increase in GH levels with no significant stimulation of ACTH or cortisol, suggesting hypothalamic specificity. Kraemer et al., Journal of Clinical Endocrinology & Metabolism 2

Elevated IGF-1 has implications for patients with certain health histories

Not recommended if you have severe liver or kidney impairment

Competitive athletes subject to drug testing should NOT use 5-amino-1MQ, as it is banned by the World Anti-Doping Agency (WADA) under the S0 category of Non-Approved Substances. Use of the compound may result in positive drug tests, sanctions, and disqualification from competition