glucuronidation glutathione reaction (a) and preferred chemical structures for Phase II Reactions - Biotransformation
Phase II Reactions Biotransformation of Drugs Glucuronidation Activity of the UGT2B17 Enzyme toward Xenobiotics Drug Metabolism and Disposition Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial Proposed scheme for the metabolic activation of diclofenac by acyl Download Scientific Diagram
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