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This mini-review aims to provide a detailed source of current information on this octapeptide

PLGA with a copolymer ratio 50:50 (Mw = 50 kDa) and PCL (Mw = 70 kDa) were purchased from Esun Industrial Company, China

In vivo studies confirmed that Ghrelin significantly activated the BMP6/SMAD1 signaling pathway in the brain tissue of AD mice, thereby inhibiting microglial ferroptosis, promoting microglial polarization toward the M2 phenotype, and ameliorating learning and memory deficits in AD mice (Guo et al., 2025b)

Here, NAD + is recognized as an essential recycling co-enzyme to maintain metabolism and cellular homeostasis (3)