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Ursodeoxycholic acid Ursodeoxycholic acid (UDCA) is well known for dissolving cholesterol stones, which can stabilize cell membranes, safeguard mitochondria, mitigate bile salt toxicity, and be employed in the treatment of primary biliary cholangitis and cholestatic liver disease

CX-4945 and TBB inhibit CK2 [28], which phosphorylates a variety of proteins that regulate DDR, circadian rhythms, cell survival, senescence, and apoptosis

Exosomes and biomimetic nanoparticles, natural or synthetic vesicles can be targeted to certain cells and are very efficient in transporting siRNAs, mRNAs, and small molecules across the blood-brain barrier

Behavioral assessments using the open-field test and tail suspension test revealed a reduction in immobility time, indicating an antidepressant-like effect