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Description

Detailed protocols for sample handling, nanoHPLC-MS/MS instrumentation parameters, and data processing methodologies are provided in the Supplementary InformationMethods section

10.1021/jm801449a J

Concern for Excess Weight Gain : Use of INSTIs, particularly bictegravir-tenofovir alafenamide-emtricitabine and dolutegravir plus tenofovir alafenamide-emtricitabine, has been associated with more weight gain after starting antiretroviral therapy as compared to older regimens, such as regimens that contain efavirenz or a boosted protease inhibitor as the anchor drug, or regimens that contain tenofovir DF as a component of the NRTI backbone