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NAFLD alleviating potential of black cumin oil has also been studied in a randomized, double-blind, placebo-controlled clinical trial, which demonstrates a reduction in FBS level, lipid profiles (TG, TC, LDL, VLDL), liver enzymes (AST and ALT), hs-CRP inflammatory marker, IL-6, TNF-, and an increase in the HDL-C levels in the interventional group compared to the placebo group [163]

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High IL-8 levels correlate with poor prognosis and chemotherapy resistance [141, 142]

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