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Opioid meds tied to higher risk of death in people with kidney disease By American Heart Association News Medication options can be limited for people with chronic kidney disease, which is why they often get prescribed opioids to help manage pain

Glutathione-dependent yield and repair of single-strand DNA breaks in irradiated cells

Differential macrophage programming in the tumor microenvironment

To address the limitations of current drug testing strategies mainly involving 2D cell cultures and animal testing, a three-dimensional microphysiological model of the human liver containing expandable human liver sinusoidal endothelial cells, monocyte-derived macrophages and differentiated HepaRG cells was utilized to investigate the toxicity of trovafloxacin and compared it to the structurally-related non-toxic drug levofloxacin