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Cagrilintide is a long-acting amylin analogue with dual amylin and calcitonin receptor activity, whereas semaglutide is a once-weekly GLP-1 receptor agonist with robust anti-hyperglycemic and appetite-suppressing effects

Plenty of people even use both, just on alternating nights so they arent competing for the same slot

Some researchers who experience inadequate appetite suppression with semaglutide alone or who are not losing weight on GLP-1 monotherapy find that the amylin pathway provides the additional appetite regulation they need

Greenhill LL, Pliszka S, Dulcan MK, Bernet W, Arnold V, Beitchman J, et al