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Researchers have studied Ta1 in patients with psoriatic arthritis, rheumatoid arthritis, and systemic lupus erythematosus, finding that it influences multiple components of the inflammatory and autoimmune cascade

decreased EpCAM expression was subsequently observed [120]

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It also influences neuronal subtype specification and regulates axonal growth, branching, and targeting in the central nervous system through interactions with HES1, a neural stem cell homeostasis molecule