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Sulfite may also be oxidized to sulfate, extra- and intracellularly by peroxidases or non-enzymatically catalyzed by metal ions or superoxide radicals and subsequently reduced and assimilated again

Originally containing the important cytosolic CXC motif, CD4 then underwent rapid evolution at two distinct protein-protein interaction sites in D1 and D2, both bearing important Cys residues

Depending on the nature of this final cleavage, the procedure can be modified to give a C-terminal acyl thiocyanate peptide product which automatically rearranges to a thiohydantoin incorporating the penultimate C-terminal unit

Statements Author contributions AT, RP, JB, BI, and YG conceived the idea and wrote the manuscript