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Glucose is consumed excessively in many developed countries and while it is essential for cellular respiration, it possesses absorption-enhancing properties that elevates intestinal permeability (Lerner and Matthias 2015a)

Because it lacks long-term human clinical trials, the full long-term side effect profile is unknown

Common Side Effects When side effects occurred, they were typically mild, transient, and similar in frequency to placebo groups: Reported Adverse Effects Most Common (occurring in small percentage of participants): Mild to moderate headaches (most frequently reported, often resolving with continued use) Injection site reactions (minor redness, swelling, or irritation at injection site) Gastrointestinal effects (particularly at higher oral doses: mild nausea, diarrhea, flatulence) Fatigue (reported occasionally during initial adaptation period) Rare Events: One case of chest tightness was deemed possibly related to treatment in safety trials