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However, an important safety concern for the development of a SARS-CoV-2 vaccine or of antibody-based therapies is the potential risk of vaccine enhancement of the disease, also known as antibody-dependent enhancement (ADE) and enhanced respiratory disease (ERD) 23

Nevertheless, further validation in larger clinical cohorts is required before such an approach can be broadly implemented

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A key protein in axonal transport is Stathmin 2 (STMN2), which aids in axonal regrowth after injury and is found to be altered specifically by the toxic accumulations of TDP-43 and is found in lower quantities in spinal cords of mouse models of ALS [202, 287]