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These approaches may include the use of topical or systemic anti-inflammatory medications, such as corticosteroids [5, 6] and nonsteroidal anti-inflammatory drugs (NSAIDs) [6], immunosuppressive therapy with agents like methotrexate or cyclosporine (CsA) [7], administration of antiviral or antibacterial agents in cases of infectious causes [8], and in certain instances, surgical intervention to address complications or unresponsive cases

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Also, recent reports suggested that those with pre-existing conditions such as diabetes, hypertension, and pulmonary, cardiac, and kidney diseases are at a higher risk of developing a severe infection [20,21,22]