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FIGURE 3 Furthermore, depletion of NAD+/NADH has been shown to leads to membrane depolarization, mitophagy and cell death via apoptosis or ferroptosis (Figure 3C clearly shows that ER induced significant polarization of both cells within 4 h of treatment

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Similar content being viewed by others Introduction Cancer is a major cause of death with more than 1.8 million new cases estimated to be diagnosed in 2020 in the United States alone 1