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Description

Metabolic reprogramming from Glycolysis to fatty acid uptake and beta-oxidation in platinum-resistant cancer cells

They include abrocitinib (Cibinqo), ruxolitinib (Opzelura), and upadacitinib (Rinvoq)

6 This suggests that much of the infused NAD+ is broken down outside cells into smaller components like nicotinamide (NAM) or ADP-ribose

Furthermore, the KEGG results revealed associations of these DEGs with pathways related to cholesterol metabolism, amino acid biosynthesis, and primary bile acid biosynthesis, among others (Figure 7D)