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Material and methods of research: Studies conducted on laboratory animals, rats, males and females

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Curcumin increases the expression of Nrf2, HO-1, and GPX4 in hepatocytes, inhibits the decline of mitochondrial membrane potential in hepatocytes, and all these changes could be reversed by ferroptosis inducer erastin, indicating that curcumin protects against Wilsons disease by inhibiting ferroptosis

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Burrows, George E

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