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doi: 10.1093/hmg/ddv273 64 AdakPBanerjeeNSinhaSBandyopadhyayAK

Hormone therapy acquired resistance occurs after the suppression of ER function with selective estrogen receptor modulators (SERMs) such as tamoxifen 75 or by lowering serum estradiol (E2) levels or blocking peripheral conversion of adrenal precursors with aromatase inhibitors