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The siP-Syn mice were also subjected to chronic hypoxia as in the previous experiments

Lyophilized powder (unopened vial): Store in a dry, desiccated environment at temperatures below 18 C, with 20 C or 80 C recommended for long-term storage

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GSK-3 phosporylates Nrf2 which leads to its ubiquitination and subsequent degradation, thus when GSK-3 is inactived Nrf2 is upregulated and leads to higher expression of antioxidative enzymes [99]