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But continuously altering systemic methylation every day for a year straight is a very different proposition, and its precisely the scenario with zero human data behind it

Collectively, this study provides a solid foundation for future exploration into the impact of NNMTi-and diet-mediated changes to the gut microbiome in obese and lean populations, as well as future targets to investigate mechanistically with NNMTi treatment

These are known as lipotropics, substances that help break down fat during metabolism in the body

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