Yilmaz M, Kantarjian H, Short N, Konopleva M, Kadia T, DiNardo C, Borthakur G , Pemmaraju N, Maiti A, Jabbour E, Issa G, Jain N, Takahashi K, Sasaki K, Ohanian M, Tang G, Loghavi S, Patel K, Garcia-Manero G, Andreeff M, Ravandi F, Daver N
Glossary ALS Amyotrophic lateral sclerosis ASB1 Ankyrin repeat and SOCS box protein 1 ATP Adenosine triphosphate BAX BCL-2-associated X protein BCL-2 B-cell lymphoma 2 CBS Cystathionine -synthase CoQ/CoQ 10 Coenzyme Q/Coenzyme Q10 CoQ 10 H 2 Ubiquinol (reduced CoQ 10 ) CRC Colorectal cancer cGAS Cyclic GMPAMP synthase cGASSTING cGASstimulator of interferon genes pathway CSE Cystathionine -lyase DHODH Dihydroorotate dehydrogenase DNA Deoxyribonucleic acid Drp1 Dynamin-related protein 1 ELOB Elongin B ETC Electron transport chain ETHE1 Persulfide dioxygenase (ethylmalonic encephalopathy protein 1) FAD Flavin adenine dinucleotide FSP1 Ferroptosis suppressor protein 1 GPX4 Glutathione peroxidase 4 GSH Glutathione GSSH Glutathione persulfide GSSSG Glutathione trisulfide H 2 S Hydrogen sulfide H 2 Se Hydrogen selenide HIF-1 Hypoxia-inducible factor-1 alpha IC 50 Half-maximal inhibitory concentration IBD Inflammatory bowel disease IFN Interferon MPST/3-MST 3-Mercaptopyruvate sulfurtransferase NaHS Sodium hydrosulfide NLRP3 NLR family pyrin domain containing 3 NQO1 NAD(P)H:quinone oxidoreductase 1 NRF2 Nuclear factor erythroid 2related factor 2 PC Pyruvate carboxylase PGC1 Peroxisome proliferator-activated receptor- coactivator-1 Qred/Qox Reduced/oxidized quinone ROS Reactive oxygen species SOD/SOD2 Superoxide dismutase/Superoxide dismutase 2 SONFH Steroid-induced osteonecrosis of the femoral head SQOR Sulfide:quinone oxidoreductase STAT3 Signal transducer and activator of transcription 3 STING Stimulator of interferon genes SUOX Sulfite oxidase TST Thiosulfate sulfurtransferase UC Ulcerative colitis xCT (SLC7A11) Cystine/glutamate antiporter References 1 AbeK.KimuraH
Its core mechanisms are closely related to disorders of cellular energy metabolism, accumulation of oxidative stress, and reduced capacity for DNA damage repair
Use within recommended period after first puncture
