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The human evidence is positive but more limited in scale than the prescription standards of care (minoxidil and 5-AR inhibitors), which have decades of large randomized controlled trials behind them

In B cells, glucocorticoids impair upstream B cell receptor and Toll-like receptor 7 signaling while promoting significant upregulation of the genes encoding the immunomodulatory cytokine IL-10 [18]

(All committee members underwent the same ethics review and vetting process required of all FDA advisory committee members, Emily Hilliard, a spokesperson for the Department of Health and Human Services, told me in an email.) The decision is only a recommendation, and the FDA would still need to sign off on an actual rule change