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Secondary endpoints were defined as pharmacodynamics and pharmacokinetic parameters including maximum serum concentration, time to maximum concentration, half-life, plasma clearance, and volume of distribution, as well as exploratory parameters including bodyweight, glycemic control, and overall hormone profile

Getting Better Results with Combination Therapies Studies comparing microneedling alone versus microneedling combined with PRP, growth factor serums, or other biologics consistently show incremental improvement with combination approaches

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