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Early intervention can make a dramatic difference in preventing the severe outcomes of alcohol abuse

By the same time, the FDA approved the use of a equimolar combination of IGF-1 and IGFBP-3 (Mecasermin Rinfabate, iPlex), suggesting that it would be a better choice, seeming as it will require lower doses because of the augmented half-life of the molecule and buffering effect on concentration

Preclinical studies suggest it promotes the formation of new blood vessels (angiogenesis) and accelerates the migration of fibroblasts involved in wound healing

Importantly, LL5 can also bind CLASP, which in turn associates with EB1 bound to the plus end of growing microtubules