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Essa MM, Bishir M, Bhat A, Chidambaram SB, Al-Balushi B, Hamdan H, et al

Current preclinical research on therapeutic strategies and human clinical trials can be divided into drugs that target the primary cause, i.e., loss-of-function mutations in MECP2 , and drugs that target downstream consequences, including neurotransmitter receptor systems, neurotrophins, and their intracellular signaling pathways (Tables 3, 4)