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Increased Risk of Toxicity with Ibuprofen in Patients with Renal Impairment: Advise patients with mild to moderate renal impairment of the risks associated with concomitant ibuprofen use and instruct them to avoid use of all ibuprofen containing products for 2 days before, the day of, and 2 days following administration of ALIMTA [see Dosage and Administration (2.5), Warnings and Precautions (5.6), and Drug Interactions (7)]

This change could exacerbate current confusion and add further uncertainty regarding the diagnosis and management of PA

doi:10.1002/acr.22096 7Mocci G, Marzo M, Papa A, Armuzzi A, Guidi L

The Reconstitution Math: Making Sense of the Numbers Now, we get to the core of the matter