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Predicted peptide structures from PepStrMod and Iterative Threading ASSEmbly Refinement aid design candidates, but predicted tertiary structures, 153 were successfully modeled, require in vivo testing

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It is likely that this autoimmune symptom is also attributed to impaired thymocyte selection, since the same disorder is associated with autosomal recessive deficiency in AIRE, a central transcription factor mediating thymocyte negative selection and central tolerance [94,95,96]

doi: 10.1016/j.jad.2020.09.073 277 ElwingJELustmanPJWangHLClouseRE