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Supplementary material The Supplementary Material for this article can be found online at: References 1 ArocaA.BenitoJ

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Gene-to-microbiome regulation contributes to disease heritability Since the gut microbiome has been revealed to play important roles in various human diseases, we next sought to establish the genetics-dependent regulatory circuits from intestinal gene expression to microbiome composition, and eventually to human complex diseases and phenotypes

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