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Abbreviations 5-FU : 5-Fluorouracil CIM : Chemotherapeutics-induced intestinal mucositis ROS : Reactive oxygen species IL : Interleukins NF-B : Nuclear factor-kappa B SLC7A11 : Solute carrier family 7 member 11 SLC3A2 : Solute carrier family 3 member 2 GSH : Reduced glutathione GPx4 : Glutathione peroxidase 4 Nrf2 : Nuclear factor erythroid-related factor 2 CAT : Catalase SOD : Superoxide dismutase MDA : Malondialdehyde FAO : Food and Agriculture Organization WHO : World Health Organization DMSO : Dimethyl sulfoxide i.p

Les donnes ont t recueillies en recherchant des informations pertinentes dans plusieurs bases de donnes, telles que PubMed, Scopus, ScienceDirect et Google Scholar

This is consistent with the idea that pH changes caused by GAPDH inhibition are not due to a general inhibition of glycolysis but specific to a block at the level of GAPDH and in part due to accumulation of upstream glycolytic intermediates

Lanzino M, Garofalo C, Morelli C, Le Pera M, Casaburi I, McPhaul MJ, et al