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Effect biomarkers can be categorized based on the time course of contaminant-organism interactions into biomarkers of early and late biological effects (NRC, 2006)

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MOF-coated MnO nanosheets were developed for the co-delivery of DZ survivin inhibitors and DOX, demonstrating enhanced tumor suppression through a combination of DZ-mediated gene silencing, chemotherapy, and ROS generation (Nie et al

Likewise, any PD treatment aimed to reduce, among others, glucose exposure may further benefit in using osmo-metabolic agents