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doi: 10.3389/fnagi.2018.00180 11 BuawangpongN.PinyopornpanishK.Siri-AngkulN.ChattipakornN.ChattipakornS

A retrospective study was performed where 20 subjects with oily skin and large pores were evaluated after intradermal onabotulinum toxin A was injected in the T-zone

The amount of cytochrome c oxidase negative muscle fibers in treated mice decreased by 30%, the citrate synthase activity in muscle as a marker of mitochondrial biogenesis was doubled, liver lipid levels were restored and muscle mitochondrial ultrastructure was normalized (no ragged red fiber-like muscle fibers or mitochondria with distorted structure and cristae on electron microscopy)

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