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Moreover, in the hypothyroid animals, many of the mast cells showed partial or complete degranulation, which was in contrast to the non-activated mast cells in the animals with normal thyroid function.[ref] Other animal studies show that hypothyroidism increases mast cell infiltration into the liver and mast cell levels in the bone marrow

Exacerbating this issue is that one of the metabolites of alcohol metabolism is acetaldehyde

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Pre-Treatment Assessment: The doctor might recommend blood tests to assess liver and kidney function since these organs play a role in metabolizing glutathione