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If you're opting for an energy drink or another beverage, seek out these forms of B12 for optimal results

Bacteria colonizing the catheter, the collection bag, or both produce a substance called indirubin, which is red, and indigo, which is blue, and they combine to make a bright purple color

Congenital transport-protein deficiencies, including transcobalamin II deficiency, are another rare cause of vitamin B 12 deficiency

Peripheral peptide hormones are released postprandially and travel in the circulation to bind to their receptors in the homeostatic regulatory centers in the CNS, notably the arcuate nucleus (ARC) of the hypothalamus and the dorsal vagal complex (DVC) in the brainstem medulla