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Importantly, these pseudo leukotrienes activated key inflammatory pathways (ERK and Akt) in bronchial epithelial cells, and this activity was blocked by CysLT receptor antagonists such as Montelukast and Zafirlukast

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Due to the lack of pigment, whilst amelanotic melanoma are classically described as skin-coloured, a substantial proportion appear as red or pink

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There is still a gap in understanding how these mechanisms interact with each other, particularly in the context of cancer

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