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Whereas deficiencies in the enzymes (through genetic manipulation or use of inhibitors) exacerbate ischemia-reperfusion (I/R) injury, overexpression of these enzymes or treatment with pharmacological donors or inhaled gas therapy have been shown to have cytoprotective effects

For successful integration, donor cells-whether developmentally immature fetal progenitors or more advanced in vitro patterned and matured cells-must adapt to the complex and highly organized architecture of the host neural network

For instance, PET scan detecting A disclosed that (1) many individuals have significant amyloid plaque burden without showing memory or cognitive impairments

J Shihezi Univ (Nat Sci)