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Due to their negative impact on the vascular endothelium and inflammatory processes, these activated oxidative stress pathways contribute to the pathophysiology of COVID-19 and Long COVID [84,85,86]

Premature leakage of electrons to oxygen can lead to production of reactive oxygen species

the endpoint may additionally be determined remotely, for example, through comparisons of photographs or other recordings by a trained medical professional or other individual

*Correspondence: Chi Wang Ip, [email protected] This article was submitted to Multiple Sclerosis and Neuroimmunology, a section of the journal Frontiers in Immunology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers