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The antioxidant action of DTPA is derived from its ability to chelate Fe 3+ and thus prevent its reaction with superoxide and hydrogen peroxide, leading to formation of hydroxyl radicals (i.e., preventing HaberWeiss and Fentons reactions) (Cohen and Sinet, 1982)

"Effects of vitamin B12, on cell proliferation and cellular alkaline phosphatase activity in human bone marrow stromal osteoprogenitor cells and UMR106 osteoblastic cells"

In preklinische modellen werd een dergelijke synergistische GH-respons beschreven, maar dit blijft onderwerp van fundamenteel onderzoek

Thus, tissue samples (from both tumor and healthy sections of the incised lung piece) were preserved from post-sampling oxidation immediately upon collection in neutrally buffered 80% methanol containing the cysteine alkylating reagent N-ethylmaleimide (NEM) following our recently published method 15 , enabling an unbiased determination of both small molecular weight (e.g., glutathione) as well as protein thiols