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(5226:) Ras-related C3botulinum toxin substrate2 precursor (p21-Rac2)(Small G protein) (GX)

(2016) 148:10351058.e3

Together with a study showing that displaced VM-progenitors with -synuclein triplication into the brain of PD rats can aggravate the disease phenotype 201 , these studies hints that direct homotopic transplantation of hMLOs may be a promising way, which can be used to explore the pathogenicity of PD by transplanting mutation-specific organoids into normal rodent models or the therapeutic effect of by grafting healthy organoids into PD-phenotypic ones

Younes A, Consoli U, Snell V, Clodi K, Kliche KO, Palmer JL, Gruss HJ, Armitage R, Thomas EK, Cabanillas F, Andreeff M