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Karav S, Le Parc A, De Leite Nobrega JM, Frese SA, Kirmiz N, Block DE, Barile D, Mills DA

Tumor necrosis factor-alpha promotes macrophage-induced vascular smooth muscle cell apoptosis by direct and autocrine mechanisms

However, they are unsuitable for large molecules, may cause dose dumping, and their drug-loading capacity depends on crystallinity and molecule size [207]