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HRV refers to the subtle, rhythmic heart rate fluctuations that occur with respiration when we breathe in our heart rate speeds up slightly and when we breathe out it slows down slightly

Our data differ from the whole animal reports in that a) only a single cell type is being analyzed under controlled conditions, b) pneumocytes, not bronchial or tracheal cells, are the focus and c) ozone exposure is within environmentally relevant levels

In a subacute toxicity study, rats showed no significant changes in behavior, gross pathology, body weight, biochemistry, or most hematological markers

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