dihexa synaptic plasticity Growth factors and their peptide mimetics for treatment of traumatic brain injury Dihexa (also known as PNB-0408)
Dihexa (also known as PNB 0408) is an experimental small molecule derived from angiotensin IV. It was engineered to cross the bloodbrain barrier and has shown synaptogenic effects in preclinical models. The often quoted Homosynaptic plasticity Wikipedia AngIV Analog Dihexa Rescues Cognitive Impairment and Recovers Memory in the APP PS1 Mouse via the PI3K AKT Signaling Pathway Frontiers Shaping inhibition: activity dependent structural plasticity of GABAergic synapses
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