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Chin Med J (Engl) 113(3):232-5, 2000

The timing of administration matters: evening dosing (30-60 minutes before sleep) capitalizes on the natural nocturnal GH pulse, potentially producing a synergistic effect with endogenous GH secretion

Recent studies have revealed that lactate production in astrocytes expresses 2 adrenergic receptors (2AR), which are integral for memory consolidation (Alberini et al., 2018)