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8 Conclusion and future perspectives This review elucidates how obesity induces OS through metabolic, endocrine, inflammatory, and gut microbiota pathways

These intracellular antioxidants are normally located within cells, cytoplasm, and organelles (e.g., mitochondria) to protect muscle fibers from ROS-induced damage (Powers and Jackson, 2008

Spinach, kale, broccoli, sunflower seeds, and nuts like almonds and hazelnuts and even peanut butter are packed with vitamin E

They include CAMP-response element binding protein (CREB), SP1 transcription factor (SP1), transcription factor AP-2 (AP2), proliferator-activated receptor alpha (PPAR), all activating GPX4 expression, while Krppel-like transcription factor 2 (KLF2) and CAMP-response element modulator (CREM), both repress its protein expression [7]