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10.1016/j.jnutbio.2021.108926 159 LeonardT

GSH may aid in improving ischemic stroke pathogenesis by reducing cerebral infarction and preventing cell death (59)

While some studies have explored the benefits of specific phytochemicals in VCI models, most rely on single animal models that fail to fully recapitulate specific clinical VCI subtypes

These may be classified, according to their mechanism of action at the intestinal lining, as direct or indirect biomarkers of gut-barrier functionality ( Table 1 )