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In parallel, hypoxia-inducible factor-1 (HIF-1), a key transcriptional regulator of VEGF, is closely linked to ovarian androgen activity

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The expression of AGXT , the gene encoding AGT, was found to be decreased via hypermethylation of the AGXT promoter in human hepatocytes isolated from steatotic livers 10 , and in livers of patients with histologically confirmed end-stage metabolic dysfunction associated steatohepatitis (MASH) 52

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The once-daily administration mode (qd): Mice were given MCTR1 (200 ng/mice, iv) 0.5 h before being subjected to CLP

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Then transfer the survival cells into a 96-well plate to expand single clones for approximately 3 weeks, genomic DNA were extracted and sequencing after PCR amplification using the following primers TLK1: F: TCACTTTGTCAGCGTGGTCA, R: CCACGGTCTGACTGCAAAAA

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