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Acetyl-L-carnitine improves pain, nerve regeneration, and vibratory perception in patients with chronic diabetic neuropathy: an analysis of two randomized placebo-controlled trials

Steenge et al

2.3 Activation of endoplasmic reticulum stress Endoplasmic reticulum (ER) is a critical organelle for protein synthesis and maturation

This figure shows that the proportion of patients achieving any particular level of improvement was consistently higher for divalproex sodium than for placebo