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Collectively, the ability of TCM-derived metabolites to address multiple pathogenic factors of CVD concurrently (as summarized in Figure 1) holds promise for treating complex cardiovascular disorders where no single molecular target is sufficient (Zhang et al., 2024)

356 Synergistic effects are observed when MSCs are combined with conventional therapies, such as GLP-1RA exenatide 357 or SGLT-2I, such as empagliflozin, 358 which improve mitochondrial autophagy, podocyte protection, and renal function in diabetic rat models

The stable carbon isotope signature of methane produced by saprotrophic fungi

Furthermore, epigenetic alterations within germ cells pose multigenerational adverse effects on the reproductive system