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Upon APAP treatment, the phosphorylation of JNK was increased in three independent Peli3 +/+ WT mice and profoundly decreased in Peli3 / KO mice (Fig

Copper(II) ions serve as essential cofactors for numerous enzymes involved in tissue repair, including lysyl oxidase (collagen cross-linking), cytochrome c oxidase (mitochondrial energy production), and superoxide dismutase (antioxidant defense)