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TB-500 operates primarily through G-actin sequestration, PI3K/Akt pathway activation, and promotion of endothelial cell and fibroblast migration , producing particularly pronounced effects on angiogenesis, cell migration into wound beds, cardiac and skeletal muscle repair, and the remodelling of extracellular matrix during tissue regeneration

The degenerative process associated with osteoarthritis creates a painful cycle where inflamed synovial tissue produces cytokines and prostaglandins that sensitise nerve endings, while swelling and effusion mechanically restrict movement [2]

Syra Aesthetics and Longevity Institute

Charleigh Kristine Schonlau, sophomore, Deans List, College of Engineering, biological systems engineering