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Main Research 1) In overweight or obese individuals, treatment with Cagrilintide was found to significantly reduce overall body weight

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Design of in vivo Experiments The animals were separated into 4 groups according to the treatment schedule, as follows: saline (saline 0.9% + cecal ligation and puncture CLP/ n = 18 animals), Ceftriaxone (Cef 20 mg/kg + CLP/ n = 6 animals), aqueous extract of Ab (Ab 135 mg/kg + CLP, n = 18 animals) and sham (surgery control, n = 18 animals)

Researchers observed this difference during meal challenge tests and when the dogs were fasting